Study Type
Interventional - Drug
completed
The objective of the RE-LY study was to demonstrate the efficacy and safety of dabigatran etexilate in patients with non-valvular atrial fibrillation for the prevention of stroke and systemic embolism.
Primary endpoint:
Incidence of stroke (including hemorrhagic) and systemic embolism.
Secondary endpointw;
Incidence of stroke (including hemorrhagic); systemic embolism; all death; Incidence of stroke (including hemorrhagic); systemic embolism; pulmonary embolism; acute myocardial infarction; or vascular deaths (including deaths from bleeding).
All primary and secondary events are adjudicated.
RE-LY Presentation - Download PDFStudy Design
Prospective, randomized, parallel-group, non-inferiority trial
NO. of Countries
44
NO. of Sites
951
NO. of Participants
18113
Study Period
2005-2009
Sponsor
PHRI
Stuart Connolly
Stuart Connolly
Stuart Connolly is a Professor of Medicine at McMaster University and a cardiac electrophysiologist at Hamilton Health Sciences. He became a faculty member at McMaster University in 1983 and was awarded a full professorship in 1994. He was also appointed as the inaugural holder of the Salim Yusuf Chair in Cardiology at McMaster University.
He has published more than 270 scientific articles in the field, and is currently a member of the editorial boards for a number of prominent cardiology journals, including Heart, the American Heart Journal and the Journal of Pacing and Electrophysiology. His main research interests are focused on the evaluation of treatments for heart rhythm disorders. His academic career has been largely devoted to the design and execution of controlled clinical trials in this area.
He holds a Masters degree from Fordham University, New York, and an MD from McGill University in Montreal. He received his specialist training in cardiology at the University of Toronto and at Stanford University.
Gayle Lewis
Gayle Lewis
completed
RE-LY ABLE
Arrhythmia & Heart Failure
The RELY-ABLE study comprised of: The long-term, multi-center extension of dabigatran treatment in patients with...
completed
RE-LY AF Registry
Arrhythmia & Heart Failure
The objective of the RE-LY AF Registry was to evaluate and document the variations in...
