Study Type
Observational - Registry
completed
PREMISE is a retrospective, observational study will evaluate the efficacy and safety of the MitraClip in real world Canadian practice. It will include all patients who have undergone MitraClip implantation in Canada to date.
PREMISE will provide valuable data to describe patient demographics, etiology of mitral regurgitation, co-morbidities, medication use and functional class.
PREMISE Slides - Download PDFStudy Design
Retrospective, multicenter, observational
NO. of Countries
1
NO. of Sites
12 target
NO. of Participants
850 target
Study Period
2018 - 2020
Sponsor
PHRI
Shamir Mehta
Senior Scientist
Shamir Mehta
Senior Scientist
Shamir Mehta is a Senior Scientist with the Acute Coronary Syndrome and Interventional Cardiology research program at PHRI, a Professor of Medicine at McMaster University, and Director of the Interventional Cardiology program at Hamilton Health Sciences. His research focuses on the role and timing of invasive therapies in patients with acute ischemic heart disease, and the evaluation of novel antiplatelet and anticoagulant therapies in these patients.
He has led several large pragmatic randomized trials evaluating invasive interventional strategies in patients with acute coronary syndromes. He has also lead multinational randomized trials evaluating novel antiplatelet and anticoagulant therapies to improve outcomes in patients experiencing a heart attack.
Shamir Mehta has published 127 original research papers in several medical journals including The New England Journal of Medicine, The Lancet, JAMA, and Circulation. His success in research has earned him a coveted Canada’s Top 40 under 40TM award in 2004, and he has received a Canadian Institutes of Health Research New Investigator Career Award.
