Study Type
Interventional - Device
completed
The objective of the PIAAF Family Practice study was to finnd Atrial Fibrillation (AF) among patients 65 years of age or older, a family practice based screening program that will be implemented using three simple methods: manual pulse check; single lead handheld ECG; and blood pressure machine with automated AF detection algorithms.
Primary outcomes:
Sensitivity, specificity, positive likelihood ratio and negative likelihood ratio of each screening test in the Family Practice setting.
Secondary outcomes:
Cost effectiveness of screening, OAC prescription rates, risk factors, and user feedback from the screening tools.
Co-Principal Investigators, with Jeff Healey of PHRI, were:
- David Gladstone, Sunnybrook Hopsital
- Noah Ivers, Women’s College Hospital
- Russell Quinn, Libin Cardiovascular Institute of Alberta
Study Design
Cohort study
NO. of Countries
1
NO. of Sites
22
NO. of Participants
2171
Study Period
2015 - 2016
Sponsor
PHRI
Jeff Healey
Senior Scientist
Jeff Healey
Senior Scientist
Jeff Healey is a Cardiologist/Electrophysiologist and Professor of Medicine at McMaster University. He is Yusuf Chair and Director of Cardiology at McMaster University. He is the chair of the Canadian Stroke Prevention and Intervention Network (CSPIN) and past chair of the Canadian Atrial Fibrillation guidelines committee. He is also on the steering committee of the international AF Screen organization.
Healey was the lead author of the ASSERT trial that demonstrated the increased stroke risk associated with sub-clinical atrial fibrillation (New England Journal of Medicine 2012), and the principal investigator of the ARTESIA trial, which demonstrated that anticoagulation with apixaban reduced the risk of stroke in patients with sub-clinical atrial fibrillation New England Journal of Medicine 2023). He is also the principal investigator of the LAAOS-4 trial, evaluating the role of left atrial appendage occlusion on top of NOAC therapy for prevention of stroke in high-risk individuals with atrial fibrillation.
Canadian Stroke Prevention Intervention Network (C-SPIN)
completed
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