Study Type
Interventional - Procedure
completed
The objective of the PAPA-CABG study was to demonstrate that it is feasible to recruit patients and to use a new test called “CT angiography” to determine whether the bypass grafts are still working or have become blocked.
Primary endpoints:
- Graft patency
- MI
- Death
- Stroke
Secondary Endpoints:
- Bleeding
- Transfusion
- Re-exploration
- Platelet function tests.
- Not adjudicated.
Study Design
Randomized, double-blind, placebo control, parallel group
NO. of Countries
1
NO. of Sites
1
NO. of Participants
150
Study Period
2007 - 2008
Sponsor
PHRI
John Eikelboom
Senior Scientist
John Eikelboom
Senior Scientist
John Eikelboom is Professor, Department of Medicine, McMaster University, Senior Scientist, Population Health Research Institute, Hamilton Health Sciences Corporation, and Hematologist, Thrombosis Service, Hamilton General Hospital. He completed training in Internal Medicine and Hematology in Perth, Australia, in 1998 and in Health Research Methodology at McMaster University, Canada, in 2000.
He has authored or co-authored more than 800 articles in peer-reviewed journals and for the past decade has been listed annually by the Web of Science among the top 1% of cited researchers. He holds the Jack Hirsh/Population Health Research Institute Chair in Thrombosis and Atherosclerosis. His current research, supported by peer reviewed funding from the Canadian Institutes for Health Research and the Gates Foundation focuses on the efficacy and safety of antithrombotic therapies in arterial, venous, cardiac, and procedure-associated thromboembolism as well as strategies to reduce the burden of the “big three” infectious diseases (HIV, TB, malaria) on the African continent.
Jessica Vincent
Program Director
Jessica Vincent
Program Director
Jessica Vincent has more than 15 years’ experience in coordinating and managing large, international clinical trials. As Associate Program Manager, she oversees interventional trials, registries, and observational research studies in the areas of perioperative medicine, cardiac surgery, and digital health.
She holds an Honours Bachelor of Science Degree from Queens University, and a Master of Clinical Epidemiology Degree from the University of Newcastle.
