Study Type
Interventional - Procedure
ongoing
The OSCAIL study is a centrally guided, locally championed pilot study to determine the feasibility of implementing key elements of organized stroke care in hospitals in low resource settings.
Primary endpoint:
To increase the proportion of patients who receive 3 or more key stroke care interventions (KSI) by at least 10%.
Secondary endpoint:
To determine whether the implementation of stroke care pathways leads to:
- A decreased proportion of patients with an m-RS of greater than 3 at discharge; and
- A decreased proportion of patients experiencing secondary complications.
Research collaborators on OSCAIL include:
- Martin Kaddumukasa (Uganda)
- Lynn Katsoulis (South Africa)
- Megha Khanna; Jeyaraj Pandian (India)
- Gerard Urimubenshi (Rwanda)
Study Design
Multi-centre, pre-post educational intervention
NO. of Countries
4
NO. of Sites
8
NO. of Participants
1120
Study Period
2017 - TBD
Sponsor
PHRI
Jackie Bosch
Scientist
Jackie Bosch
Scientist
Jackie Bosch is the Assistant Dean of the McMaster Occupational Therapy Program and a PHRI Scientist. She has a Bachelor’s degree in Occupational Therapy, a Master’s degree in Clinical Epidemiology and Biostatistics, and a PhD in Rehabilitation Science. She also serves as a Professor in the School of Rehabilitation and has an Adjunct Appointment with the University of Galway College of Medicine, Nursing, and Health Sciences.
Her research focuses on improving functional outcomes in clinical trials, particularly for stroke survivors in low-resource settings, and enhancing clinical trial methods. Bosch has taken on leadership roles in large-scale trials such as HOPE, HOPE-TOO, HOPE-3 (NCT00468923), DREAM (NCT00095654), ORIGIN (NCT00069784), TIPS-3 (NCT01646437), and COMPASS (NCT01776424). She leads the Organized Stroke Care Across Income Levels (OSCAIL) group, which has conducted a proof-of-concept study implementing key aspects of stroke unit care in hospitals within low-resource settings. Currently, the OSCAIL group is working on a community-based study aimed at improving outcomes for stroke survivors in these challenging environments. Bosch is also interested in optimizing how clinical trials are conducted, especially by finding new ways to make the start-up and execution processes more efficient.
Jackie Bosch has published 184 articles and received several awards, including the Lorna Reimer Award for Leadership from the Canadian Occupational Therapy Foundation in 2019 and the Faculty of Health Sciences, McMaster University, Programs Award for Graduate Students in 2014.
