completed

The DEPOSITION Pilot trial hypothesized that topical intra-pericardial (i.p.) application of Tranexamic Acid (TxA) versus intravenous (i.v.) will reduce postoperative bleeding in patients who have undergone cardiac surgery using cardiopulmonary bypass (CPB), and decrease or eliminate the risk of seizures.

Study Type

Inteventional - Drug

Study Design

Single-centre randomized controlled trial

NO. of Countries

1

NO. of Sites

1

NO. of Participants

97

Study Period

2017-2018

Sponsor

PHRI

McMaster Surgical Associates (MSA) Grant

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