Study Type
Interventional - Drug
The objective of the ACCORD study was to test treatment strategies aimed at reducing cardiovascular events in type 2 diabetes.
The trial was designed to test the effects on major CVD events of:
On February 6, 2008 the intensive arm of ACCORD was stopped and all intensive glycemia participants were “transitioned” to the standard glycemia arm of the trial due to an increase in mortality. All other arms continued as per protocol.
Primary endpoints:
Reduction in blood pressure
Reduction in heart rate
Modify lipids
Secondary endpoint: Platelet aggregation. Not adjudicated
PHRI was the Canadian coordinating centre for ACCORD, managing the 13 sites in Canada. Hertzel Gerstein was the Principal Investigator for Canada, and sat on the Steering Committee for ACCORD study.
Interventional - Drug
Randomized, multicenter, double 2X2 factorial design
2
77
10251
2001-2009
National Heart, Lung and Blood Institute
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