Recent Publications

PURE, INTERHEART, INTERSTROKE: Variations in risks from smoking between high-income, middle-income, and low-income countries: an analysis of data from 179 000 participants from 63 countries

The Lancet Global Health

S Thirunavukkarasu, KK Teo, P Britz-McKibbin, B Gill, S Islam, G Pare, S Rangarajan, M Duong, F Lanas, P Lopez-Jaramillo, PK Mony, Lakshmi Pinnaka, VR Kutty, A Orlandini, A Avezum, A Wielgosz, P Poirier, KF Alhabib, A Temizhan, J Chifamba, K Yeates, IM Kruger, R Khatib, R Yusuf, A Rosengren, K Zatonska, R Iqbal, W Lui, X Lang, S Li, B Hu, AL Dans, AH Yusufali, A Bahonar, MJ O'Donnell, M McKee, S Yusuf

January 2022

PURE: Developing indicators of age-friendly neighbourhood environments for urban and rural communities across 20 low-, middle-, and high-income countries

BMC Public Health

EJ Rugel, CK Chow, DJ Corsi, P Hystad, S Rangarajan, S Yusuf, SA Lear

January 2022

ORCHID: Characterizing frailty in myeloproliferative neoplasms

Leukemia Research

NLJ Chornenki, DM Siegal, K Quar, S Woolgar, S Rangarajan, S Karampatos, DP Leong

January 2022

GWAS and ExWAS of blood Mitochondrial DNA copy number identifies 71 loci and highlights a potential causal role in dementia

eLife

M Chong, P Mohammadi-Shemirani, N Perrot, W Nelson, R Morton, S Narula, R Lali, I Khan, M Khan, C Judge, T Machipisa, N Cawte, M O'Donnell, M Pigeyre, L Akhabir, G Paré

January 2022

Direct oral anticoagulants versus warfarin in patients with atrial fibrillation: patient-level network meta-analyses of randomized clinical trials (including RE-LY) with interaction testing by age and sex

AHA Circulation

AP Carnicelli, H Hong, SJ Connolly, J Eikelboom, RP Giugliano, DA Morrow, MR Patel, L Wallentin, JH Alexander, MC Bahit, AP Benz, EA Bohula, TF Chao, L Dyal, M Ezekowitz, KAA Fox, B Gencer, JL Halperin, Z Hijazi, SH Hohnloser, K Hua, E Hylek, ET Kato, J Kuder, RD Lopes, KW Mahaffey, J Oldgren, JP Piccini, CT Ruff, J Steffel, D Wojdyla, CB Granger

January 2022

ANNEXa-4: Andexanet alfa for specific anticoagulation reversal in patients with acute bleeding during treatment with edoxaban

Thrombosis and Haemostatis Journal

AP Benz, L Xu, JW Eikelboom, S Middeldorp, TJ Milling Jr., M Crowther, P Yue, P Conley G Lu, SJ Connolly

January 2022

POISE-3 substudy: Effect of a perioperative hypotension-avoidance strategy versus a hypertension-avoidance strategy on the risk of acute kidney injury: A clinical research protocol for a substudy of the randomized clinical trial

Canadian Journal of Kidney Health and Disease

AX Garg, M Cuerden, H Aguado, M Amir, EP Belley-Cote, K Bhatt, BM Biccard, FK Borges, M Chan, D Conen, E Duceppe, S Efremov, J Eikelboom, E Fleischmann, L Giovanni, P Gross, R Jayaram, M Kirov, Y Kleinlugtenbelt, A Kurz, A Lamy, K Lesilie, V Likhvantsev, V Lomivorotov, M Marcucci, MJ Martinez-Zapata, M McGillion, WF McIntyre, C Meyhoff, S Ofori, T Painter, P Paniagua, C Parikh, J Parlow, A Patel, C Polanczyk, T Richards, P Roshanov, D Schmartz, D Sessler, T Short, JM Sontrop, J Spence, S Srinathan, D Stillo, W Szczeklik, V Tandon, D Torres, T Van Helder, J Vincent, CY Wang, M Wang, R Whitlock, M Wittmann, D Xavier, PJ Devereaux

January 2022

REWIND: Dulaglutide and incident atrial fibrillation or flutter in patients with type 2 diabetes – a post-hoc analysis from the randomized trial

Diabetes, Obesity and Metabolism

PJ Raubenheimer, WC Cushman, A Avezum, J Basile, I Conget, G Dagenais, A Hoover, P Jansky, F Lanas, LA Leiter, P Lopez-Jaramillo, N Pogosova, J Probstfield, P Rao-Melacini, L Ryden, WHH Sheu, T Temelkova-Kurktschiev, H Gerstein

January 2022

CAHHM: Normal sex and age-specific parameters in a multi-ethnic population: a cardiovascular magnetic resonance study of the Canadian Alliance for Healthy Hearts and Minds cohort

BMC Journal of Cardiovascular Magnetic Resonance

JM Luu, C Gebhard, C Ramasundarahettige, D Desai, K Schulze, F Marcotte, P Awadalla, P Broet, T Drummer, J Hicks, E Larose, A Moody, EE Smith, JC Tardif, T Teixeira, KK Teo, J Vena, DS Lee, SS Anand, MG Friedrich

January 2022

RADICAL-PC substudy: Low-serum testosterone in men with newly diagnosed androgen-deprivation therapy-naive prostate cancer and its relationship to cardiovascular risk factors

The Journal of Urology

JH Pinthus, WCM Duivenvoorden, L Klotz, SD Mukherjee, R Siemens, T Niazi, V Fradet, W Foster, E Duceppe, D Taussky, R Hamilton, L Lavallee, I Brown, J Chin, D Gopaul, A Wassef, W Kassouf, M Davis, PD Violette, S Agapay, K Balasubramanian, R Mian, S Rangarajan, A Sener, B Shayegan, PJ Devereaux, DP Leong

January 2022

ECLA PHRI COLCOVID: Effect of colchicine vs usual care alone on intubation and 28-day mortality in patients hospitalized with COVID-19

JAMA Network Open

R Diaz, A Orlandini, N Castellana, A Caccavo, P Corral, G Corral, C Chacon, P Lamelas, F Botto, ML Diaz, JM Dominguez, AP Ing, CR Lic, A Galatte, F Scarafia, O Sued, O Gutierrez, SS Jolly, JM Miro, J Eikelboom, M Loeb, AP Maggioni, DL Bhatt, S Yusuf

December 2021

TIPS-3: The cost implications of a polypill for primary prevention

European Heart Journal - Quality of Care and Clinical Outcomes

A Lamy, W Tong, P Joseph, P Gao, P Pais, P Lopez-Jaramillo, M Walli-Attaei, T Dans, D Xavier, S Talukder, A Santoso, H Gamra, S Yusuf

December 2021

PURE: Variations in the association of height with mortality, cardiovascular disease and cancer in low-, middle- and high-income countries

International Journal of Epidemiology

AK Khetan, DP Leong, R Gupta, Y Zhu, S Li, W Liu, IM Kruger, KK Teo, A Wielgosz, R Yusuf, NA MN Khan, R Khatib, KF Alhabib, K Karsidag, J Chifamba, N Mohammadifard, P Seron, P Lopez-Jaramillo, A Orlandini, A Szuba, A Yusufali, S Nair, A Rosengren, K Yeates, AM Dans, R Iqbal, A Avezum, S Rangarajan, S Yusuf

December 2021

PURE: Psychosocial risk factors and cardiovascular disease and death in a population-based cohort from 21 low-, middle-, and high-income countries

JAMA Network Open

A Santosa, A Rosengren, C Ramasundarahettige, S Rangarajan, J Chifamba, SA Lear, P Poirier, KE Yeates, R Yusuf, A Orlandini, L Weida, L Sidong, Z Yibing, V Mohan, M Kaur, K Zatonska, N Ismail, P Lopez-Jaramillo, R Iqbal, LM Palileo-Villanueva, AH Yusufali, KF AlHabib, S Yusuf

December 2021

PURE-Air: Multinational prediction of household and personal exposure to fine particulate matter (PM2.5) in the PURE cohort study

Environmental International

M Shupler, P Hystad, A Birch, YL Chu, M Jeronimo, D Miller-Lionberg, P Gustafson, S Rangarajan, M Mustaha, L Heenan, P Seron, F Lanas, F Cazor, MJ Oliveros, P Lopez-Jaramillo, PA Camacho, J Otero, M Perez, S Yusuf, M Brauer

December 2021

The Lancet Global Health

BMC Public Health

Leukemia Research

eLife

AHA Circulation

Thrombosis and Haemostatis Journal

Canadian Journal of Kidney Health and Disease

Diabetes, Obesity and Metabolism

BMC Journal of Cardiovascular Magnetic Resonance

The Journal of Urology

JAMA Network Open

European Heart Journal - Quality of Care and Clinical Outcomes

International Journal of Epidemiology

JAMA Network Open

Environmental International

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