Janice Pogue Lectureship in Biostatistics

Named for the late Janice Pogue, the founder of PHRI's statistical group, this lectureship invites international leaders to share their knowledge in biostatistics.

December 5, 2024

2024 Janice Pogue Lecture
Dr. Frank Harrell

Dr. Harrell received his PhD in Biostatistics from the University of North Carolina in 1979. He was on the faculty of Duke University for 17 years and of the University of Virginia for 7 years. He founded the Division of Biostatistics and Epidemiology at the University of Virginia School of Medicine in 1996 and the Department of Biostatistics at Vanderbilt University in 2003. He has taught biostatistics and research methodology to hundreds of physicians since 1980 and has been a mentor or co-mentor to several physician investigators. He is an Associate Editor for Statistics in Medicine. His specialties are development of accurate prognostic and diagnostic models, model validation, clinical trials, observational clinical research, technology evaluation, quantifying predictive accuracy, missing data imputation, pharmaceutical safety, flexible Bayesian design and analysis, and statistical graphics and reporting.

Dr. Harrell is a Fellow of the American Statistical Association and winner of its 2014 WJ Dixon Award for Excellence in Statistical Consulting. He was the 2008 Mitchell Lecturer for the Department of Statistics, Glasgow University. He was the 2012 Presidential Invited Lecturer for WNAR, International Biometric Society, the 2017 Visionary Speaker, Clinical Studies Coordinating Center, University of North Carolina Department of Biostatistics, Chapel Hill, and the 2018 Distinguished Visiting Scientist, University of Calgary Biostatistics Centre.

He has worked in cardiovascular research and statistical computing for 50 years and is the author of a popular text Regression Modeling Strategies, an accompanying R package rms, several other R packages, and free online texts Biostatistics for Biomedical Research and R Workflow.

Dr. Harrell will be addressing the following topics:

  • Modernizing Clinical Trial Design and Analysis to Improve Efficiency & Flexibility
  • Bayesian Thinking with a variety of examples how different it is from traditional statistics

Past Events

October 16, 2023

David L. DeMets
2023 Janice Pogue Lectureship in Biostatistics

Max Halperin Emeritus Professor of Biostatistics, former Chair of the Department of Biostatistics and Medical Informatics at the University of Wisconsin – Madison. Former chief of the Biostatistics Branch at the National Heart, Lung and Blood Institute at the National Institutes of Health.

Research interests include the design, data monitoring and analysis of clinical trials, especially large Phase III randomized clinical trials. He is well known for his work on sequential statistical methods for monitoring interim data for early evidence of intervention benefit or possible harm.

Janet Wittes

June 28, 2022

Janet Wittes
2022 Janice Pogue Lectureship in Biostatistics

Founder and President Emerita of WCG Statistics Collaborative, Janet Wittes is a Fellow of the American Statistical Association, the Society for Clinical Trials, and the American Association for the Advancement of Science, and an elected member of the International Statistical Institute.

Interim Analyses: Rules or Guidelines: A guide from and for the perplexed

December 1, 2020

Monica Taljaard
2020 Janice Pogue Lectureship

Senior Scientist, Clinical Epidemiology Program, University of Ottawa
Associate Professor, School of Epidemiology and Public Health, University of Ottawa

The Promise and Pitfalls of Stepped Wedge Cluster Randomized Trials Watch the recorded lectureship.

January 1, 2019

Lisa M. LaVange
2019 Janice Pogue Lectureship

Professor and Associate Chair, and Director of Collaborative Studies Coordinating Center, University of North Carolina

Opportunities and Challenges in Clinical Research with the Use of Big Data and Novel Trial Designs

January 1, 2018

Amy H. Herring
2018 Janice Pogue Lectureship

Professor of Statistical Science & Research Professor of Global Health, Duke University

Challenges in Modeling Associations Among Environmental and Behavioural Exposures and Health Outcomes

January 1, 2017

Thomas Fleming
2017 Janice Pogue Lectureship

Professor of Biostatistics – University of Washington

Use of Biomarkers as Replacement Endpoints in Clinical Trials

Arnold L. Johnson Lectureship in Cardiology

Named for renowned Canadian cardiologist, Dr. Arnold L. Johnson, PHRI's lectureship series started in 1995.

October 3, 2022

2022 Arnold L. Johnson Lectureship in Cardiology
Bertram Pitt

Bertram Pitt is a Professor of Medicine Emeritus, University of Michigan, School of Medicine. He obtained his MD degree from the University of Basel in Switzerland, and completed a fellowship in cardiology at the Johns Hopkins University School of Medicine where he remained on the faculty until he left to direct the division of cardiology at the University of Michigan.

New Opportunities for Mineralocorticoid Receptor Antagonists (MRAs) Alone and in Combination in Cardiorenal Disease

Past Events

January 29, 2020

Calum A. MacRae
2020 Arnold Johnson Lectureship in Cardiology

Vice Chair for Scientific Innovation, Department of Medicine, Brigham and Women’s Hospital | Harvard Medical School

Creating Learning Health Systems to Integrate Care, Translation and Discovery

  • A Practical Approach to the Use of Genetics in the Clinical Management of Cardiovascular Disease
  • Changing the Scale of Biomedical Research in a Digital Era

January 1, 2018

Robert A. Harrington
2018 Arnold Johnson Lectureship in Cardiology

Arthur L. Bloomfield Professor of Medicine

Chairman of the Department of Medicine

Stanford University

Key ACS Lessons over the Last 25-30 Years Education and Research in an Era of Quality, Big Data, Precision Medicine, and Digital Health Rethinking Randomized Trials

January 1, 2017

Sir Rory Collins
2017 Arnold Johnson Lectureship in Cardiology

Head of Nuffield Department of Population Health

BHF Professor of Medicine and Epidemiology

University of Oxford

Fellow of the Academy of Medical Sciences Fellow of the Royal Society

Randomization vs. Observation: Statin Therapy in the Real World Evolve or Die: The Urent Need to Streamline Randomized Trails

January 1, 2016

Milton Packer
2016 Arnold Johnson Lectureship in Cardiology

Distinguished Scholar in Cardiovascular Science, Baylor Heart and Vascular Institute

Baylor University Medical Center

Historical Paradigms for Understanding Heart Failure: An Exploration of How Many Times We Have Been Wrong Neprilysin Inhibitors

January 1, 2015

Hugh Watkins
2015 Arnold Johnson Lectureship in Cardiology

Head, Radcliffe Department of Medicine

Professor of Cardiovascular Medicine, University of Oxford

Honorary Consultant in Cardiology, John Radcliffe Hospital

Director, British Heart Foundation

Centre of Research Excellence at Oxford

Genomic Medicine - Hype or Hope? Genetic Insights that Impact on Diagnosis and Treatment in Hypertrophic Cardiomyopathy

January 1, 2014

John McMurray
2014 Arnold Johnson Lectureship in Cardiology

Professor of Cardiology, Institute of Cardiovascular and Medical Sciences, University of Glasgow
Inaugural Eugene Braunwald Scholar in Cardiovascular (CV) Disease, Brigham and Women’s Hospital

Success in Heart Failure Understand the latest advances in pharmacological therapy for HF-REF Understand the latest advances in device therapy for HF-REF c) Understand the latest therapeutic efforts in HF-PEF

January 1, 2013

Eugene Braunwald
2013 Arnold Johnson Lectureship in Cardiology

Distinguished Hersey Professor of Medicine, Harvard Medical School

Lessons from Recent TIMI Trials on Diabetes and Atrial Fibrillation Top 10 Achievements in Cardiology

January 1, 2012

Thomas F. Lüscher
2012 Arnold Johnson Lectureship in Cardiology

Professor & Chairman, Cardiology & Cardiovascular Center University Hospital Zurich

From Eisenhower’s Heart Attack to Modern Management of Acute Coronary Syndrome Aging and Longevity Genes as Mediators of Cardiovascular Disease

January 1, 2011

Harry R. Buller
2011 Arnold Johnson Lectureship in Cardiology

Professor of Internal Medicine Specialized in Vascular Medicine Academic Medical Center Amsterdam

Management of Venous Thromboembolism – The Hamilton Legacy Treatment of Venous Thromboembolism Relation Venous and Arterial Thrombosis and the Role of Statins

January 1, 2009

Peter Sleight
2009 Arnold Johnson Lectureship in Cardiology

Honorary Consultant, John Radcliffe Hospital, Oxford, UK

For AMI, thrombolysis is now dead - but has it been murdered? Serendipity in Medical Careers - can it still occur? Role of circulatory rhythms in health & disease: Music, mantras & prayer  

January 1, 2008

Robert Hart
2008 Arnold Johnson Lectureship in Cardiology

Professor, Department of Neurology, University of Texas Health Sciences Center

Atrial Fibrillation and Stroke: The First 100 Years What’s New in Stroke? The Top 10 Studies for 2006 -2008

January 1, 2007

John Camm
2007 Arnold Johnson Lectureship in Cardiology

Professor, Clinical Cardiology Cardiac and Vascular Sciences

St. George’s Hospital, London, UK

Acquired QT Prolongation and Cardiovascular Risk New Antiarrhythmic Drugs for Atrial Fibrillation

Dr. Terence Montague

January 1, 2006

Terrence Montague
2006 Arnold Johnson Lectureship in Cardiology

Professor of Medicine and Director, Disease Management, University of Montreal

Canada's Health: Perceptions, Politics and Possibilities Patient Adherence and Concordance in Chronic Care Disease Management as a Chronic Model: A Cardiologist's View

January 1, 2005

Sir Richard Doll
2005 Arnold Johnson Lectureship in Cardiology

Emeritus Professor of Medicine, University of Oxford

Nuffield Department of Clinical Medicine

Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Oxford, UK

Proof of Causality Deduction from Epidemiological Observation Tobacco: A Medical History Quantification of the Benefits of Alcohol: An Epidemiological Problem Clinical Discussion of Major Projects with Investigators Identification of Tobacco as One of the Great Killers

January 1, 2004

Philip James
2004 Arnold Johnson Lectureship in Cardiology

Director, Public Health Policy Group & Chairman, International Obesity Task Force (IASO/OTF)
London, UK

Challenges and Controversies in the Management of Chronic Diseases: The Case of Obesity Managing the New Epidemic of Obesity The Sensitivity of Asians to the Co-Morbidities of Weight Gain The High Global Burden of Disease from Obesity

January 1, 2001

Sir Richard Peto
2001 Arnold Johnson Lectureship in Cardiology

Emeritus Professor, Medical Statistics and Epidemiology, Nuffield Department of Population Health

University of Oxford, UK

Halving Premature Death Getting the BP Story Right Future Worldwide Health Effects of Current Smoking Patterns

January 1, 2000

Richard Horton
2000 Arnold Johnson Lectureship in Cardiology

Editor-in-Chief, The Lancet

The Journalism of Science: Justifiable Controversy or Jeopardized Credibility?

Population Health Sciences Lectureship

PHRI's lectureship focusing on world experts in population health, including work in public health, genomics, global health, and more.

November 15, 2022

2022 PHRI Lectureship in Population Health Sciences
Carol Brayne

Carol Brayne is a Professor of Public Health Medicine at the University of Cambridge. Her research programme is based around longitudinal population-based studies of people aged 65 and above, running since 1985. They include collections of blood, and are linked to the Cambridge Brain Bank.

Topic: How can population based research into brain health and dementia inform public health action for future health in general?

Past Events

January 1, 2019

Mark Lathrop
2019 Population Health Sciences Lectureship

Scientific Director, McGill University Genome Québec Innovation Centre

Understanding the Genetic Basis of Human Health and Disease Can Genetics Improve Healthcare?

January 1, 2017

Richard Horton
2017 Population Health Sciences Lectureship

Editor-in-Chief, The Lancet

Planetary Health: A Global Science for the 21st Century

January 1, 2016

Giuseppe Mancia
2016 Population Health Sciences Lectureship

Professor Emeritus, University of Milano-Bicocca, Italy
President, European Society of Hypertension (ESH) Foundation / Chairman, ESH Educational Board

What are the Practical Implications of Recent Trials for the Practicing Clinician to Reduce Cardiovascular Disease in Hypertension?

January 1, 2015

Stephen MacMahon
2015 Population Health Sciences Lectureship

Principal Director, The George Institute for Global Health

Professor, Cardiovascular Medicine & Epidemiology, University of Sydney

Professor of Medicine, James Martin Fellow, University of Oxford

Professor of Public Health, Peking University

High blood pressure - what to do about the world’s leading cause of illness Innovation, entrepreneurship and global health What do physicians and supermarket checkout assistants have in common? Imminent extinction by computer!

January 1, 2014

Simon Capewell
2014 Population Health Sciences Lectureship

Professor & Chair of Clinical Epidemiology, Public Health & Policy, University of Liverpool

Preventing Cardiac Deaths in Canada: Past and Future NCD Prevention Politics: Pills or Policies? Science or Showbiz? Using the Media to Support your Public Health Interventions

January 1, 2013

George Davey Smith
2013 Population Health Sciences Lectureship

Professor – University of Bristol

Director of the MRC Centre for Causal Analyses in Translational Epidemiology

The Limits of Personalised Medicine: Epidemiological Reflections Mendelian randomization in cardiovascular disease: what does the future hold?

January 1, 2011

Martin McKee
2011 Population Health Sciences Lectureship

London School of Hygiene and Tropical Medicine

Looking Upstream: New perspectives from around the world on the social and environmental influences of health

PHRI Perioperative Care Lectureship

Focusing on innovation and collaboration in the efforts to reduce global perioperative risk.

November 1, 2023

2023 Perioperative Care Lectureship
Christian Mueller

Full Professor of Cardiology, Faculty of Medicine; Director of the Cardiovascular Research Institute Basel (CRIB), University Hospital Basel, Switzerland. 

 

Topic: Novelties in the early diagnosis of AMI: possible implications for perioperative care

Location: David Braley Research Institute, Hamilton, ON.

Time: 5:00 pm – 6:30 pm

RSVP to heather.gill@phri.ca

Past Events

February 24, 2020

Beverley Orser
2020 Perioperative Care Lectureship

Chair of the Department of Anesthesiology and Pain Medicine; Professor of Anesthesia and Physiology – University of Toronto. Former Canada Research Chair in Anesthesia

Preserving Brain Function after Anesthesia and Surgery: To understand the incidence and risk factors associated with postoperative neurocognitive deficits; to learn about the new nomenclature for postoperative neurocognitive deficits and recent practice guidelines; and to identify mechanisms underlying postoperative neurocognitive deficits and potential new treatments.

January 1, 2014

Alison Halliday
2014 Perioperative Care Lectureship

Professor of Vascular Surgery, University of Oxford, UK

40 Years of Carotid Interventional Trials: Where we will be in 10 years' time?

January 1, 2012

Paul Myles
2012 Perioperative Care Lectureship

Professor, Department of Anesthesia, Monash University, Melbourne, Australia

Large Multicentre Trials in Anesthesia

January 1, 2014

Greg Hirsch
2011 Perioperative Care Lectureship

Cardiac Surgeon, Dalhousie University, Halifax Nova Scotia, Canada

Improving Cardiac Surgery Outcomes: Kaizen or Report Card Day

Special PHRI Lectures

Beyond the scope of PHRI's regular lectureship series, these exceptional speakers from around the world grace us with their research insights and innovations.

March 27, 2021

2021 Special PHRI Lecture
David Moher

Dealing with Predatory Journals:
How to identify and avoid predatory journals, and how to support research integrity

Wednesday, March 24, 2021
8:00 – 9:15 am EST

Speaker: Dr. David Moher, PhD, is the Director, Centre for Journalology at the Ottawa Hospital Research Institute, and a Professor in the School of Epidemiology and Public Health, University of Ottawa.

Professor Moher received his PhD in clinical epidemiology and biostatistics, from the Amsterdam Medical Centre, University of Amsterdam. Professor Moher’s current research foci is open scholarship, and trustworthiness in research.

Past Events

March 8, 2021

Nadine Caron
2021 Special PHRI Lecture

9th Annual Chanchlani Global Health Research Award and Lecture – part of a virtual 2021 International Women’s Day event

Canada’s first female First Nations surgeon, Dr. Nadine Caron is the founding First Nations Health Authority Chair (FNHA) in Cancer and Wellness at the University of British Columbia, where she also serves as co-director of the university’s Centre for Excellence in Indigenous Health (CEIH). Her main focus is Aboriginal Health and Canadian health policy and her work advocates for the needs and voices of northern, rural and Indigenous populations in Canada.

Topic: Perspectives of a First Nations Physician in Canada: Do you ever wonder what we think?

12 -4 pm EST, Monday, March 8th, 2021

Additional event speakers include:

  • Dr. Zena Samaan – Associate Professor, Department of Psychiatry and Behavioural Neurosciences, McMaster University
  • Dr. Harriet MacMillan – Chedoke Health Chair in Child Psychiatry, McMaster University
  • Dr. Claudia Emerson – Director and Associate Professor, Institute on Ethics & Policy for Innovation, McMaster University

More about the half-day online event.

February 1, 2020

Jonathan Patz
2020 Special PHRI Lecture

Professor and Director, Global Health Institute, University of Wisconsin-Madison
Lead author, United Nations Intergovernmental Panel on Climate Change (IPCC)

Can actions to solve today’s climate crisis create the largest health opportunity of our times?

  • Multiple exposure routes through which climate change threatens our health
  • Why actions to mitigate greenhouse gas emissions are so urgent, across all sectors
  • How climate change mitigation policies in the energy, food, and transportation sectors can reduce the global burden of chronic diseases
Watch the video recording of this lecture.

May 1, 2019

Stuart Spencer
2019 Special PHRI Lectures

Associate Editor, The Lancet

Cardiovascular Research in The Lancet: Past, Present and Future What Makes a High-Quality Paper?

February 1, 2019

Camara Phyllis Jones
2019 Special PHRI Lectures

Senior Fellow, Satcher Health Leadership Institute and Cardiovascular Research Institute

Adjunct Associate Professor, Community Health and Preventative Medicine, Morehouse School of Medicine

Chanchlani Global Health Research Award Recipient for 2019

Naming, Measuring and Addressing the Impacts of Racism on Health View Video

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