COMPASS
COMPASS is a randomized controlled trial of rivaroxaban for the prevention of major cardiovascular events in patients with coronary artery disease (CAD) or peripheral arterial disease (PAD).
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The primary objective is to determine whether, on a background of optimal medical therapy with low dose ASA and ticagrelor, a strategy of multi-vessel revascularization involving staged...
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The CORONARY trial, led by PHRI Scientist Andre Lamy, was named a landmark development in the history of CABG by JACC.
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The objective of HOPE was to evaluate the use of the ACE inhibitor, ramipril, and of vitamin E in high-risk patients with chronic stable vascular disease and/or diabetes and additional risk factor(s).
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To evaluate whether a cholesterol lowering drug, rosuvastatin, and a combination blood pressure lowering pill, candesartan/ hydrochlorothiazide, used alone or together can reduce the risk of heart attack...
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The INTERHEART study found that nine easily measurable and modifiable risk factors could explain more than 90 per cent of the risk of a heart attack globally and in all regions and major ethnic groups of the world.
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Stroke is the most common cause of adult disability and the third leading cause of death worldwide, most of which occurs in low-income countries.
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The objective of the LAAOS III study is to determine if removing the left atrial...
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To assess the impact of dabigatran (a direct thrombin inhibitor) in patients suffering myocardial injury after noncardiac surgery (MINS).
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To evaluate the efficacy and safety of clopidogrel when given with aspirin patients with non- ST-segment elevation acute coronary syndromes.
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To evaluate the effects of lantus (insulin glargine) versus standard care, and of Omega-3 fatty acids versus placebo, in reducing cardiovascular morbidity...
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An international multi-centre randomized clinical trial to assess the impact of tranexamic acid (TXA) versus...
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The PURE study examines the impact of urbanization, modernization and globalization on the development of risk factors , and CVD.
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To demonstrate the efficacy and safety of dabigatran etexilate in patients with non-valvular atrial fibrillation, for the prevention of stroke and systemic embolism.
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To demonstrate the efficacy and safety of dabigatran etexilate in patients with non-valvular atrial fibrillation for the prevention of stroke and systemic embolism.
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The objective of the TIMACS study was to compare relative efficacy, safety, and cost effectiveness...
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The objective of the TIPS-3 study is to evaluate a polypill (with and without aspirin)...
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Two large trials, prior to the TOTAL study, had reported contradictory results at one year...
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To collect international data regarding major adverse vascular events. during non-cardiac surgery.
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